The Prequel Formulas That Will Help Strengthen Your Skin Barrier

The Prequel Formulas That Will Help Strengthen Your Skin Barrier
If you have sensitive or reactive skin, you'll know the fear that comes with trying new skincare - and too often, the products deemed 'safe' for you can feel decidedly uninspiring. Prequel was created to challenge that trade-off, combining dermatologist-developed formulas with textures and packaging that are every bit as considered and buzz-worthy as the ingredients inside.

It’s the passion project of Dr. Sam Ellis, a board-certified medical and cosmetic dermatologist from the United States. She calls her approach BASIC+: “We start with tried-and-true dermatologic ingredients and elevate them through thoughtful formulation, refined textures, and an exceptional user experience. I wanted to create a line of solution-focused products formulated to optimise skin health, be safe for those with chronic skin conditions, and provide an elevated user experience.”

If skincare made to support even the most difficult skin - without sacrificing the pleasure of your routine - sounds like a fit for you, meet the brand's must-try products, now at Space NK.

The Prequel Products You Need To Know About

01

Prequel

Gleanser, £ 20,00

The Bestselling Cleanser
If you only try one product, make it the Gleanser. Made with 50% glycerin (read: ultra-hydrating), prebiotic inulin and oat extract, this bestselling face and body gel cleanser removes every last trace of makeup, SPF and grime without leaving your face feeling dry. In fact, it almost feels like you've just applied a lightweight moisturiser rather than washed it off.

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02

Prequel

Universal Skin Solution Dermal Spray, £ 19,00

The Gym Bag Essential
Hypochlorous acid neutralises acne-causing bacteria to help prevent breakouts before they start, and Prequel's version comes in a lovely fine mist that helps calm reactive, sensitised or compromised skin. Plus, it’s earned the stamp of approval from the eczema, rosacea and psoriasis associations.

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03

Prequel

Multi-Acid Milk Peel AHA Exfoliating Solution, £ 25,00

The Skin Softener
A milky serum formulated with exfoliating acids, including 15% glycolic, phytic, malic, mandelic and lactic acid, plus enzymes and squalane, working together to smooth, soften and brighten skin without overwhelming your skin barrier. And with its generous size, you won't feel precious about using it on uneven skin on your arms and legs too.

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04

Prequel

Multi-Quench Plumping Hydration Serum, £ 30,00

The Hero Hydrator
Everyone loves the healthy glow this serum gives, but if your skin is persistently dry, it's a must-try. Polyglutamic acid is known to hold even more moisture in your skin than hyaluronic acid, working at multiple molecular weights to hydrate and plump from within. Osmolytes deliver immediate hydration the moment you apply it, while glycerin works over time to restore and strengthen your skin barrier.

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05

Prequel

AM/PM Modern Moisturizer, £ 20,00

The Everyday Moisturiser
No need for separate morning and night moisturisers, this does-it-all cream keeps skin comfortable with ceramides and hydrators, including glycerin, polyglycerides and vitamin F, that strengthen your barrier and lock in hydration.

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Read More

What is Double Cleansing?
How To Repair a Damaged Skin Barrier
The Benefits of Ceramides For Skin
The Best Hyaluronic Acid Serums for Plump, Hydrated Skin
The Best Moisturisers for Dry Skin to Instantly Hydrate
Posted: Tuesday, 14 July 2026

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